Category Archives: Oncology

Multispectral Optoacoustic Tomography (MSOT) can now more reliably detect early stages of inflammation

GERMANY, Mar-30-2017 — /EPR HEALTHCARE NEWS/ — Ulcerative colitis and Crohn’s disease are the most common inflammatory bowel diseases (IBD). Globally, more than 4 million people suffer from recurring inflammation of the intestinal mucosa. To date, non-invasive methods have not been able to detect these forms of IBD reliably. Researchers at the University Hospital Erlangen (Germany) have now shown for the first time how Multispectral Optoacoustic Tomography (MSOT) can more reliably detect early stages of inflammation when compared with other non-invasive diagnostic methods. These results have recently been published in the New England Journal of Medicine.

Evaluating the inflammatory activity of the intestines early and accurately helps to prevent complications associated with IBD and guide an optimal therapy regime. Currently, doctors frequently rely on an invasive endoscopy procedure to assess the intestinal mucosa of patients with IBD. Additionally, non-invasive imaging methods are increasingly used in the clinic. For example, ultrasound allows clinicians to examine the structure, thickness and blood perfusion of the intestinal wall with changes in perfusion patterns indicating an onset of inflammation.

“With the MSOT procedure, we additionally use laser light, by which we can detect inflammation earlier than previously possible with ultrasound”, explains Prof. Dr. Maximilian Waldner, Professor at the University Hospital Erlangen. “The earlier we detect signs of an upcoming flare – i.e., a change in blood content – the quicker we can react and start a preventive treatment”. The MSOT technology was developed by iThera Medical in Munich, and was first used on IBD patients last year.

The researchers of the University Hospital Erlangen have recently published their results in the renowned New England Journal of Medicine. “We examined 108 patients with Crohn’s disease using the MSOT technology and compared the results to established non-invasive diagnostic procedures as well as endoscopy and histology”, says Prof. Waldner. “We were able to demonstrate that hemoglobin values in the tissue measured with MSOT indicate very accurately the inflammatory activity in the intestines. The method appears to be superior to other non-invasive procedures, as MSOT for the first time was able to detect even low levels of inflammation without having to perform endoscopy”.

Dr. Ferdinand Knieling, a physician at the University Hospital Erlangen, adds: “We are hoping that this principle can be applied to many applications and, in particular, also be used to enable safe evaluations of children and adolescents. With this new examination method, many of the currently invasive procedures might become obsolete.”

In optoacoustic imaging, the physician scans the intestines transabdominally through the skin, applying pulsed laser light in the near-infrared region. The energy of the light absorbed in tissue is converted into acoustic signals which are then acquired by an ultrasound detector. Christian Wiest, CEO of iThera Medical, comments: “MSOT is a new diagnostic imaging modality that can detect changes in tissue composition associated with a variety of diseases, without the use of contrast agents. The technology has already been applied in other clinical feasibility studies, e.g. for the detection of melanoma metastasis in sentinel lymph nodes or for the assessment of suspicious breast lesions”.

The results of the IBD study at the University Hospital Erlangen were published on March 30th 2017 in the New England Journal of Medicine (Volume 376, Issue 13, pg.1292-1294).

SOURCE: EuropaWire

Coalition For The Advancement Of Brachytherapy

The Coalition for the Advancement of Brachytherapy (CAB) has reviewed recent media reports stemming from a study originally presented in December 2011 by physicians associated with the University of Texas MD Anderson Cancer Center. The study compared the efficacy of whole breast irradiation (WBI) to accelerated partial breast irradiation (APBI), including the use of brachytherapy to treat select patients with early stage breast cancer. CAB believes that the methodology used in the MD Anderson study is misleading as it utilizes a Medicare billing claims database that does not include patient risk stratification data and therefore is not appropriate to use to compare outcomes and toxicities of ABPI to that of whole breast irradiation (WBI).

The treatments examined utilize different methodologies for delivering radiation therapy following surgery for the treatment of breast cancer. APBI delivers a targeted radiation therapy to select low risk patients over a five-day period. Whereas WBI delivers a broader radiation therapy whereby the entire breast is treated over the course of 30-40 days. The conclusions reached regarding the relative efficacy of the two forms of treatments are based completely on a retrospective study of insurance billing claims. This retrospective study fails to take into account key patient clinical characteristics, including, but not limited to pathology and staging, which determine risk assignment of a patient. Further, the billing code data was collected from patients treated from 2000 through 2007. Since that time, advances in brachytherapy product design, physics planning and delivery of dose have led to greater precision and accuracy of radiation treatment with improved outcomes.

CAB contends that it is impossible to draw any meaningful comparisons or conclusions without taking into consideration patient risk assessments. Counter to the findings in the MD Anderson study are multiple peer-reviewed publications available supporting the safe and effective use of APBI in appropriately selected patients. The safety and effectiveness of APBI is further supported by the fact that the American Society of Radiation Oncology (ASTRO) reaffirmed its Consensus Statement in 2011 endorsing the use of APBI in appropriately selected patients. The ASTRO APBI Consensus Statement was originally issued in 2009 based on an exhaustive search of the available medical literature in combination with expert opinion and public comment.

More recent data from a trial comprising over fourteen hundred breast cancer patients, presented on May 5, 2012 at the American Society of Breast Surgeons (ASBrS) Annual Meeting, found that APBI is equally effective, if not more effective, in preventing local breast cancer recurrence than WBI. * This trial’s findings not only contradict the MD Anderson data in finding that tumor control in the breast appears to be similar for APBI and WBI, but suggest that disease control at the initial tumor site may be better with APBI.

Michael Krachon, CAB Chair notes, “The MD Anderson study is by no means sufficient to condemn a promising procedure like APBI brachytherapy. As we await results of the randomized NSABP-B39 Phase III Trial comparing WBI to APBI, physicians should be mindful of the many positive peer-reviewed publications analyzing the efficacy and toxicity associated 2 1455 Pennsylvania Ave. NW, Suite 250, Washington, D.C. 20004 with APBI brachytherapy. The technique has been endorsed by ASTRO in appropriately selected patients, and physicians must take into account the clinical presentation of the patient and their own clinical judgment in the safe and appropriate use of this treatment modality.”

For more information contact: Richard White, Roberti + White at (202) 624-0395

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International Masters Publishers, Inc., On Behalf Of Its Collection Of Health And Well-Being Products Has Made A Donation To Rocking The Road For A Cure, Inc.

International Masters Publishers, Inc., on behalf of its collection of Health and Well-being products has made a donation to “Rocking the Road for a Cure, Inc.” — a non-profit organization founded to provide free education and support services for women and men going through the diagnosis and treatment of breast cancer.

Reflecting their strong commitment to providing valuable health information, International Masters Publishers, Inc. (IMP) recently announced its continuing support for breast cancer research and wellness programs through its contribution to the community-based non-profit organization “Rocking the Road for a Cure, Inc.”

Founded by Dawn Frey after she was diagnosed with breast cancer, “Rocking the Road for a Cure, Inc” provides free support services aimed to enhance the coping skills of those in treatment, and expand the support networks that have proven so essential to their quality of life. These services include:

• Homebound Yoga, Reiki and massage
• Medical case management assistance
• Homebound Recreational Therapy
• Beauty consultations
• Nutrition advice and services

“We are proud to support the great work done by Rocking on the Road for a Cure, Inc.”, says Dilenia Chireno, IMP Spokesperson, “their programs use many of the same approaches to self-empowerment we cover in our collections, so it’s really an excellent fit for us. We are so proud to be part of this important and worthwhile cause.”

In addition to its generous corporate donation, IMP will also offer some customers of The Complete Guide to Natural Healing and Enhancing Your Mind Body Spirit the opportunity to make an additional donation by contributing a portion of the proceeds it receives from these two products to this great cause.

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The Facts About Heart Disease

  • Heart Disease has been the number 1 killer in the US every year since 1900 with the exception of 1918.

  • At least 250,000 Americans die of heart attacks each year before they reach the hospital.

  • Every 34 seconds someone in the US dies from Heart Disease.

  • Heart Disease can be avoided with good nutrition.
If you are as little as 10 pounds overweight you are at risk forHeart Disease.Chronic Diseases cost the US economy 1.3 trillion dollars annually and this could reach 6 trillion by the middle of the century.

Reduce the Risk of Heart Disease for you and your loved ones. Over and over again I hear success stories of how people who have used our science based, nutritional products to lose weight. But not only do they lose weight but they are lowering their cholesterol levels, stabilizing blood pressure and sugar levels and are getting off of medications they have been taking for years. We have had people say they have gotten rid of allergies, migraines, joint pain and more. Good Nutrition allows your body to heal. (individual results vary). You can gain weight, lose weight, or maintain weight with our products. Our products do come with a guarantee.

My mother and father have both had open heart surgery. It is not a fun thing to go through. The thought of having your breast bone broken in half and raised in vertical position for hours is not a pretty picture to me. I do not wish to ever need this surgery and I am here to help you, in hopes that you do not ever need it as well.

Good Nutrition affects everything:

  • health

  • energy

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The American Medical Association has said that 70% of medical conditions are diet related.

Here are a few common diseases that may be prevented with proper diet and or maintaining a healthy weight.

Cancer: breast, uterus, cervix, colon, esophagus, pancreas, kidney and prostrate
Coronary Heart Disease, Diabetes, Dyslipidemia, hypertension
Idiopathic Intacraial hypertension, stroke, cataracts
Osteoarthritis, skin, gout, phlebitis
Gynecologic Abnormalities, abnormal menses,infertility, poly cystic ovarian syndrome
Gall Bladder Disease
Pulmonary Disease
Obstructive Sleep Apnea
Hypo ventilation Syndrome
Severe Pancreatitis
Non Alcoholic Fatty Liver Disease

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Once you get started with our Core Nutrition or Weight Loss Program you may find that you are saving money on your prescriptions plus doctor and hospital bills. You may even be earning more money because you are missing work less and are able to work longer hours.

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Field Fisher Waterhouse has recovered compensation for the cost of a claimant’s hospice care in a case that is though to be the first of its kind

Field Fisher Waterhouse (FFW), the full service European law firm, has recovered the value of the hospice care that was required by a claimant. This is thought to be the first case of its kind, with most hospices generally exclusively funded by charitable donations. As part of the settlement, the firm was able to recover £12,500 to be paid over to the hospice.

The case arose out of the death of a 64 year old man due to mesothelioma, an asbestos-related cancer, in December 2007 after spending his final days being cared for in a North London Hospice dedicated to cancer patients.

Through his life the man suffering from the cancer had worked as a carpenter, painter and labourer. In 1963, whilst employed as a painter for J Murphy & Sons Ltd, he was exposed to asbestos dust whilst sanding down and filling in walls in prefabricated housing containing asbestos. He was then exposed to further asbestos when working for the same company at a factory in Dagenham, cleaning debris from the guttering on roofs made from corrugated asbestos.

In August 2005 he was diagnosed with mesothelioma, an asbestos related cancer on the lining of one of his lungs. He was eventually admitted to the hospice where he spent the last month of his life.

Rodney Nelson-Jones, partner in the Asbestos Claims Group at Field Fisher Waterhouse, was instructed to claim compensation on behalf of the man’s family. The firm was able to recover £170,000 from J Murphy & Sons Ltd, £12,500 of which is being paid to the hospice which provided him with care worth over £400 a day.

This is thought to be the first time that compensation has been recovered for a patient’s hospice care, which is usually funded by charitable donations. It has long been possible to recover compensation for the value of care provided by relatives but FFW’s innovation has been to extend this principle to charitable care provided by hospices. The firm plans to continue to claim the cost of hospice care in future mesothelioma cases.

Rodney Nelson-Jones commented: “We are delighted to have been able to secure extra funding for the hospice. Hospices do a wonderful job and rely on charitable donations to provide much needed palliative care for cancer patients. We hope that this case will mean that they are now provided with an additional source of funding.”

About Field Fisher Waterhouse
Field Fisher Waterhouse LLP is a full-service European law firm with offices in Brussels, Hamburg and London. With 119 partners, over 200 other lawyers and nearly 300 support staff, FFW assist a wide range of international clients, advising across a full range of legal issues.

The main areas of practice are corporate and commercial, IP and technology, banking and finance, regulatory and real estate. Field Fisher Waterhouse LLP also have particular expertise in competition & EU law, dispute resolution, employment, asbestos and mesothelioma claims, personal injury cases and clinical negligence, public sector and tax.

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