Tag Archives: anti-ageing

Cambridge Micelle Technology in Carocelle® Lycopene and Resveratrol anti-ageing and cardio-protective formula

Cambridge, England, 2017-Feb-14 — /EPR HEALTHCARE NEWS/ — Resveratrol and lycopene are the compounds known for anti-ageing and cardio-protective properties. Mediterranean diet based, among others, on consumption of big quantities of lycopene-rich vegetables coincides with a longer lifespan, lower incidence of CVDs and reduced occurrence of some forms of cancer among the population of Mediterranean region. High resveratrol consumption is considered a factor in “French Paradox”, where epidemiological data show low incidence of CVDs, despite high consumption of saturated fats. Consumers have enormous choice of food supplements including lycopene and resveratrol, but key information is often missing: what happens to the substance once consumed and how much of it is really absorbed?

Resveratrol – the powerful anti-ageing, antioxidant polyphenol

Resveratrol is a phytochemical from polyphenols family, compounds known for their antioxidant properties. It is produced by plants in response to different stresses from their surrounding environment and found mainly in the peel and seeds of red grapes, also in peanuts and berries. High resveratrol consumption is considered a factor in “French Paradox”, where epidemiological data show apparent disconnect between the incidence of cardiovascular diseases in French population and high consumption of saturated fats. It is thought to be related to high consumption of red wine that contains resveratrol. There is significant scientific research on the beneficial effects of resveratrol relating to anti-ageing and longevity – activation of sirtuin enzymes, support of mitochondrial metabolism, protection of telomeres, antioxidant properties. It also supports cardiovascular health and influences glucose metabolism management.

Lycopene – great contributor to healthy skin

Lycopene belongs to family of plant-derived substances – carotenoids. Due to their strong antioxidative properties carotenoids help protect plants from oxidative damage caused by various stressing factors. Scientific interest in lycopene originates from the phenomenon of the Mediterranean diet and its’ cardio-protective and longevity promoting properties. The Mediterranean diet is based, among others, on high consumption of tomatoes and other vegetables that contain high levels of lycopene and other carotenoids. The population of the Mediterranean region has a longer lifespan, lower incidence of cardiovascular diseases and lower occurrence of some forms of cancer. Because of its’ antioxidative properties lycopene helps fight against free radicals in the skin, reduces its’ sensitivity to UV radiation, reduces mitochondrial DNA damage, lowers the risk of heart diseases.

Carocelle® presents best in class lycopene and resveratrol anti-ageing supplement

The main challenge of resveratrol supplementation remains its’ bioavailability. As quickly as it is absorbed from intestinal tract to bloodstream most of it is transformed into inactive compounds. New Carocelle® Lycopene & Resveratrol formulation delivers superior bioavailability, proven in clinical trials. Carocelle® technology makes resveratrol over +500% more bioavailable than other products on the market and provides its’ outstanding concentration that would normally be difficult to obtain from other available sources.

Pharmacokinetic tests for Carocelle® Lycopene have also confirmed 2x higher concentration of lycopene in the bloodstream (bioavailability) in comparison to reference brand available on the market, with the same dosage of the compound.

Carocelle® Technology behind compounds’ superior bioavailability

Vesicle-micellisation helps carotenoids become more resistant to degradation in the highly acidic stomach environment. This ensures that more active lycopene and resveratrol can pass to the intestines and be absorbed. The vesicle-micelle format is easily transformed in the intestines by bile acids to the mixed micelles. This guarantees optimal absorption of fat-soluble ingredients, like lycopene and resveratrol. The result is increased delivery of active lycopene and resveratrol to the intestine for maximum absorption, improved bioavailability and remarkable bioactivity. Chaperone compounds in Carocelle® Lycopene & Resveratrol vesicle-micelles additionally contribute to increased bioavailability of both lycopene and resveratrol.

There are currently 3 SKUs within Carocelle® range:

Carocelle® Lycopene & Resveratrol
Carocelle® Lutein & Zeaxanthin
Carocelle® Lycopene

For more information please visit www.carocelle-technology.com or contact us at contact@carocelle-technology.com

COMPANY PROFILE
Carocelle Cambridge Micelle Technology™ was founded in 2015 in collaboration with UK biotech firm Lycotec, headed by Dr. Ivan Petyaev. The company invents proprietary formulations and products that are scientifically tested and proven in laboratories in Cambridge, UK. Carocelle Cambridge Micelle Technology™ has its headquarters in Cambridge and operates a network of partnerships with research and commercial partners around the world.

DR. IVAN MIKHAILOVICH PETYAEV, MD, PHD
Dr. Petyaev is a medical doctor, researcher and author of scientific publications and inventions with applications in diagnostics, analytics, prevention and treatment of a variety of diseases. He spent his research years at MRS and Cambridge University in the Department of Pathology. To take his discoveries into innovative healthcare products he left University and set up his own company, Lycotec Limited. Dr Petyaev has wide experience of driving his innovations through the product development phase, clinical validation and in the setting up of industrial production of the successful prototypes. His projects have been supported by Cambridge University, the MRC, Papworth and Addenbrooke’s Hospitals, the British Heart Foundation, the Department for Trade and Industry and the Eurostars Eurica Project.

Via EPR Network
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Nutrition Experts Come Together For Roundtable At The Royal Society Of Medicine

Nutrition experts come together for roundtable at the Royal Society of Medicine.

AmeriSciences AS10, the first ever super-league multivitamin and nutritional formula developed from joint research with NASA and the Johnson Space Centre, will be available off the shelf in the UK from today. Key figures from the field of nutrition attended a roundtable at the Royal Society of Medicine, including the Institute for Optimum Nutrition and The Nutrition Society, to discuss how the AmeriSciences AS10 range of products will pave the way for the next generation of breakthrough technology in nutritional supplementation.

Six years of ground breaking research with NASA and the Johnson Space Centre has also indicated the potential of AmeriSciences AS10 formula to provide daily protection from low level radiation exposure. The findings, published in the Radiation Research Journal, reveal the potential of this multi-nutrient cocktail to combat the effects of stressors such as radiation, and prolong life in subjects exposed to those stressors.

Space Act Agreement 2005
In 2005, AmeriSciences and NASA and the Johnson Space Centre entered into a Space Act Agreement to develop nutritional supplements for astronauts to meet the needs of long-duration spaceflight as well as conditioning here on Earth. In 2009, the resulting AmeriSciences and NASA formulas were used and tested aboard the Space Shuttle and International Space Station with positive and exciting results.

Says Carlos Montesinos, AmeriSciences Director of Scientific and Regulatory Affairs,“The AmeriSciences AS10 product line poses a significant challenge to the current supplement market. Indeed, the strength of the antioxidant and multivitamin formulas have been so significant in testing that it will change the way nutritional supplementation is viewed in both the scientific community and general population.”

What is it?
AmeriSciences AS10 is a powerful antioxidant and anti-ageing liquid beverage, comprising a unique formulation of only 100% fruit and vegetable-derived ingredients, including the new ‘superfruits’ acai, cupuaçu and acerola sustainably sourced from the Brazilian rainforest. AmeriSciences AS10 is also part of a wider range of nutritional supplements including AS10 Life multivitamin; derived from the same joint research with NASA and the JSC for achieving optimum nutrition.

AmeriSciences AS10 product line provides a reassuring ‘safety net’ of vitamins and minerals essential for maintaining optimum health and one of the Government recommended ‘five-a-day’ portions of fruit and vegetables. The range includes an oral solution and tablet food supplements and the price reflects six years of research, with the solution retailing at £120 a month and the multivitamin tablets at £27.

Who is AmeriSciences AS10 for and how is it taken?
AmeriSciences AS10 formula, which comes in a wine-bottle shaped container, is designed for anyone feeling run-down, with hectic lifestyles or susceptible to nutritional deficiencies. Recent case report studies conducted at independent sites have demonstrated positive effects on skin health, including significant reduction in wrinkles, age spots and UVA damage. The solution is taken twice daily in 60ml doses, equivalent to four tablespoons. AS10 life is a combination of vitamins, minerals and phytonutrients in a tablet form.

An industry leader in its research and self-imposed quality standards, AmeriSciences requires that its supplements maintain a minimum of 95% dissolution rate compared to a 50% estimated market average and 75% USP requirement. Carlos Montesinos adds,“AmeriSciences’ AS10 line is just another way in which AmeriSciences is pushing the technology of the industry forward for the benefit of the consumer.”

Where is it available?
AmeriSciences products are only sold through independent AmeriSciences distributors. The Harley Medical Group is one of the major UK stockist for AmeriSciences AS10 and the further range of nutritional supplementation products developed from joint research with NASA and the Johnson Space Centre. AmeriSciences AS10 is available through the Harley Medical Group online at www.harleymedical.co.uk and at any of their 31 clinics nationwide.

Industry response
Dr Duncan Gould, GP, Men’s Health Expert and consultant pharmaceutical physician, said: “As a doctor, I am excited by the joint research and results on AmeriSciences AS10 with NASA and the Johnson Space Centre. The outcomes to date are insightful and demonstrate a prevention of the negative effects of radiation in mice by improving mortality rates: I look forward to seeing any similar data that may emerge from studies in man. The translation of such data into the human setting may have the potential to impact upon the way oncology patients are treated in the future and
may have a positive impact upon individuals who have been affected by radiation contamination, and are at high risk in the future.”

Says Bernice Berry, Associate Director of Training and Personnel Development, The Harley Medical Group, major distributor of AmeriSciences AS10 in the UK, “Before patients have cosmetic surgery they need to be in peak physical condition – as with any surgical procedure – and the AmeriSciences AS10 products will be invaluable in supporting our patients’ pre-operative preparation and post-operative recovery. For our non-surgical patients optimum nutrition is paramount as this is reflected in their outward appearance; glowing skin, strong hair and nails and an energy boost are just some of the benefits seen by our patients following use of these products. Many are particularly excited about the anti-ageing properties of range, which compliments our non-surgical treatment options.

Via EPR Network
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